Updated: Apr 16
Sonya Sotomayor, an Associate Justice of the Supreme Court of the United States, once said, "My diabetes is such a central part of my life... it did teach me discipline... it also taught me about moderation... I've trained myself to be super-vigilant... because I feel better when I am in control (Jain, 2019)."
Diabetes is a serious health condition that affects millions of people world-wide. In 2018, the CDC reported that 10.5% of the US population had diabetes, a percentage that continues to increase with age, as about 26.8% of all Americans above the age of 65 were diagnosed with diabetes. Dr. John Burd, CEO and Founder of Lysulin, Inc., was inspired by growing diabetes statistics and diabetes diagnoses in his own family. Throughout his career, Burd has founded many tools and supplements to help support people with diabetes, and is most notably known for leading Dexcom's popular conintuous glucose monitors (Woolsey, 2019). His latest addition to diabetes support is Lysulin, an all-natural supplement that blends lysine, zinc, and Vitamin C to help maintain a healthy balance of A1c blood sugar levels (Lysulin, n.d.).
Lysulin's composition is based on clinical research that suggests that the combination of lysine, zinc, and Vitamin C can not only support blood sugar levels but also prevent complications from excess glucose. According to a study conducted by Sapienza University of Rome (1993), D-lysine can bind with excess glucose and pass out of the body through the urine. Clinical trials conducted by Tehran University of Medical Sciences (2016) found that the test group taking L-lysine reduced the advanced glycation end products created by excess glucose in the system.
Burd's pilot study of Lysulin found that lysine, combined with zinc, supports beta cells in the pancreas. Studies suggest vitamin C lowers hemoglobin A1c through antioxidant activity, significantly reducing hemoglobin A1c in subjects with Type 2 diabetes and improving systolic/diastolic blood pressure (Burd, Noetzel, Gonzalez, & Melero 2018).
While there is data that supports the effectiveness of Lysulin, Burd acknowledges that Lysulin will not work for everyone. In Burd's pilot study, 14 subjects saw improvements while 6 were "non-responders", meaning they saw no effects (Burd, Noetzel, Gonzalez, & Melero 2018). "Burd points out that prescription drugs don’t work for 100% of patients, but rather the success rate he claims varies between 30 and 50%, so he’s happy if Lysulin can work for 76% of people (Dubois, 2019)."
Lysulin is currently certified by VeganMed's Animal-Free Certification. This Certification uses laboratory testing to certify that a product is free of animal-derived ingredients. Since the FDA mandates animal testing during the research portion of new drug development, medicines and supplements are not vegan. However, VeganMed can ensure that there are no animal ingredients in the final product.
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Burd, John F, et al. “Lysulin®: A Double-Blind Placebo Controlled Pilot Study of Daily Oral Supplementation in People with Type 2 Diabetes.” Diabetes Management, Open Access Journals, 31 Dec. 2018, www.openaccessjournals.com/articles/lysulin-a-doubleblind-placebo-controlled-pilot-study-of-daily-oral-supplementation-in-people-with-type-2-diabetes-12867.html.
CDC. “National Diabetes Statistics Report.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, 14 Feb. 2020, www.cdc.gov/diabetes/data/statistics/statistics-report.html.
Jain, Chitra. “World Diabetes Day, 2019: 10 Motivational Quotes to Lift up Your Spirit and Feel Happy.” Republic World, Republic World, 14 Nov. 2019, www.republicworld.com/lifestyle/health/world-diabetes-day-10-motivational-quotes-to-lift-up-your-spirit.html.
Lysulin. “Nutritional Support to Help Maintain Healthy A1c Levels.” Lysulin, lysulin.com/.
Mirmiranpour, H, et al. “The Preventive Effect of L-Lysine on Lysozyme Glycation in Type 2 Diabetes.” Acta Med Iran, vol. 54, no. 1, 1 Feb. 2016, pp. 24–31., http://acta.tums.ac.ir/index.php/acta/article/view/5385.
Sensi, M., et al. “d-Lysine Reduces the Non-Enzymatic Glycation of Proteins in Experimental Diabetes Mellitus in Rats.” Diabetologia, vol. 36, no. 9, 1993, pp. 797–801., doi:10.1007/bf00400352.
Woolsey, Brittany. “Carmel Valley Resident a Serial Entrepreneur in Diabetes Care.” Del Mar Times, Del Mar Times, 5 Feb. 2019, www.delmartimes.net/news/sd-cm-nc-0207-john-f-burd-20190130-htmlstory.html.