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Jasmine Uchi, PharmD

Wearable Heart Failure Treatment: Furoscix (furosemide) 80 mg/10 mL for Subcutaneous Use

Furoscix (furosemide) injection, manufactured by scPharmaceuticals, has been approved to help adults manage congestion caused by fluid overload in chronic heart failure. This innovative treatment utilizes a special formulation of furosemide delivered through an On-Body Infusor, providing an 80-mg dose that mirrors the effects of intravenous diuretics.


What is Furoscix?

FUROSCIX is an at-home treatment for fluid buildup associated with heart failure, designed for easy use with or without a caregiver. It delivers furosemide, a commonly used diuretic, through a wearable device, providing a quick reset of the patient’s body fluid levels. The treatment is not intended for chronic use or as a replacement for daily oral diuretics.

How does Furoscix work?

FUROSCIX is provided as a comprehensive kit delivered directly to patients’ homes. The kit includes:

●      The FUROSCIX Instructions for Use

●      One cartridge of medicine

●      A one-time-use device that is preset for your treatment

●      Alcohol wipes

The FUROSCIX On-Body Infusor administers a fixed dose of 80 mg of furosemide over approximately five hours. This device delivers the medication just under the skin (subcutaneously). When activated, a small needle inserts into the skin to administer the medication. The On-Body Infusor signals once all the medication has been delivered. Upon removal from the skin, a needle cover automatically extends to prevent accidental needle sticks.


See full instructions for FUROSCIX On-Body Infusor here.


Side Effects of Furoscix

Potential side effects of Furoscix may include:

●      Lose excess water and electrolytes (dehydration)

●      Low blood pressure (lightheadedness, dizziness)

●      High blood sugar

●      Loss of hearing (ringing in ears)

●      Sensitivity to sunlight

●      Administration site and skin reactions (bruising, redness, swelling, and infusion site pain)


Cost of Furoscix

The out-of-pocket cost can vary depending on the pharmacy and any available discounts. FUROSCIX Direct offers services to help reduce out-of-pocket costs for eligible patients, including co-pay support and patient assistance programs. A FUROSCIX Direct representative can provide more detailed information about your options.


Furoscix vs. Lasix

FUROSCIX and Lasix are both medications that contain the active ingredient furosemide. FUROSCIX achieved similar drug levels as IV furosemide but it is administered through the skin. Your care team should give you directions on how to take your oral diuretics during and after treatment with FUROSCIX. 

Drug Name

Furoscix

Lasix

Active Ingredient

Furosemide

Furosemide

Inactive Ingredient

Hydrochloric acid for pH adjustment if

needed, sodium chloride (5.84 mg), sodium hydroxide for pH adjustment if needed, tris HCl (7.88 mg), and

water for injection (q.s.)

Lactose monohydrate, magnesium stearate, starch, corn, talc, silicon dioxide

Dosing

80 mg per 10 mL

Oral Dosing: 20-600 mg per day

IV/IM Dosing: 20-200 mg per dose, with potential higher doses in some cases.

Formulation

Subcutaneous (SC)

Orally (tablets), Intravenous (IV), Intramuscularly (IM)

Indication

Treatment of congestion due to fluid overload in adults with chronic heart failure

Edema, hypertension

Administration

Outpatient setting

Hospital or outpatient setting

Read the full Furoscix package insert here.


Conclusion

Furoscix represents an advancement in the management of congestion due to fluid overload in adults with chronic heart failure. By offering a convenient at-home treatment option through a wearable On-Body Infusor, it provides congestion relief without hospital visits, enhancing patient comfort and compliance. As the medical community continues to embrace such technologies, Furoscix stands out as a promising solution for managing heart failure symptoms effectively and efficiently.


 

Disclaimer: The product and/or information provided on VeganMed is of a general nature and is not intended to be a substitute for professional medical advice, diagnosis, or treatment. We do not lab test the products to confirm that they are free from animal ingredients, and it is possible that the formulation and ingredients could have changed. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or product. The information provided in this post is accurate and up to date as of the date it was written. However, please note that circumstances and facts may change over time, and new information may become available that could alter the accuracy or relevance of the content. We encourage readers to verify and cross-reference any information provided here with trusted sources or consult relevant professionals for the most current and accurate updates.

 

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